Medicube EGF NAD+ Firming Serum
Firm, smooth, and revitalise tired-looking skin with next-generation peptide and NAD+ care.
The Medicube EGF NAD+ Firming Serum is a lightweight firming serum designed to target visible signs of ageing, including fine lines, loss of elasticity, enlarged-looking pores, uneven texture, and dullness.
Powered by EGF (sh-Oligopeptide-1), NAD+, Collagen, Niacinamide, Adenosine, and a Multi-Peptide Complex, this fast-absorbing serum helps improve the appearance of firmness and elasticity while supporting smoother, brighter, more youthful-looking skin across both the face and neck.
The formula also combines Ectoin, Glutathione, Sodium Hyaluronate, Copper Tripeptide-1, and a Superberry Antioxidant Complex to hydrate, condition, and protect the appearance of skin exposed to everyday environmental stressors. It is fragrance-free, alcohol-free, non-comedogenic tested, and suitable for daily morning and evening use.
✨ Why You'll Love It
Visibly firms and improves elasticity
EGF works alongside Copper Tripeptide-1, Palmitoyl Tripeptide-5, Collagen, and additional peptides to help skin appear firmer, smoother, and more resilient.
Helps smooth fine lines and wrinkles
Adenosine and the peptide-rich formula help soften the appearance of visible lines, including areas around the forehead, eyes, smile lines, mouth, and neck.
Powered by EGF + NAD+
The formula contains 2.5 ppm EGF (sh-Oligopeptide-1) and 1 ppm NAD+ (Nicotinamide Adenine Dinucleotide) as part of its intensive vitality and well-ageing complex.
Brightens dull, tired-looking skin
Niacinamide and Glutathione help improve the appearance of uneven tone and dullness for a fresher, more radiant complexion.
Helps refine the look of pores and texture
Regular use helps improve rough, uneven-looking skin texture and the appearance of enlarged pores.
Hydrates without heaviness
Sodium Hyaluronate, Glycerin, Xylitol derivatives, and Ectoin help maintain moisture while the lightweight water-serum texture absorbs quickly into the skin.
Antioxidant-rich Superberry Complex
A blend of berry extracts—including Blueberry, Cranberry, Raspberry and other antioxidant-rich fruits—complements the formula's radiance and skin-conditioning benefits.
Easy to add to your routine
The formula is non-comedogenic tested, primary skin-irritation tested, and free from artificial colourants. Medicube lists it for all skin types, including sensitive, dry, oily, and combination skin.
🎯 Skin Concerns
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Fine lines and wrinkles
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Loss of firmness and elasticity
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Sagging-looking skin
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Enlarged-looking pores
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Rough or uneven skin texture
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Dull, tired-looking complexion
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Dryness and dehydration
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Early and visible signs of ageing
💕 Perfect For
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All skin types
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Mature or ageing skin
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Skin beginning to lose firmness and elasticity
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Dull or uneven-looking complexions
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Dry and dehydrated skin
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Oily and combination skin
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Skin with enlarged-looking pores
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Those looking for lightweight peptide skincare without a rich or greasy texture
Medicube also states that the serum is non-comedogenic and suitable for oily, combination, and troubled-looking skin.
🌿 Key Ingredients
EGF / sh-Oligopeptide-1 – 2.5 ppm – A peptide featured in the formula to support smoother, firmer, and more youthful-looking skin.
NAD+ – 1 ppm – Nicotinamide Adenine Dinucleotide is included as part of Medicube's vitality-focused well-ageing complex to help revitalise the appearance of tired, ageing skin.
Multi-Peptide Complex – Includes Copper Tripeptide-1, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-1, Acetyl Octapeptide-3, Hexapeptide-11, and additional oligopeptides to support firmness and smoother-looking skin.
Niacinamide – Helps brighten dullness, improve uneven-looking tone, and refine the appearance of pores.
Adenosine – Helps improve the appearance of fine lines and wrinkles for smoother-looking skin.
Sodium Hyaluronate – Helps attract and retain moisture for softer, plumper, more hydrated-looking skin.
Ectoin – A skin-conditioning ingredient that helps support moisture and protect the appearance of skin against environmental stress.
Glutathione – An antioxidant ingredient that complements the formula's brightening and radiance-focused care.
Collagen Extract – Helps condition the skin and support a supple, plump, more elastic-looking complexion.
🫧 How to Use
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After cleansing and toning, apply 2–3 drops of serum to the face and neck.
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Gently spread evenly along the skin's texture.
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Lightly pat until fully absorbed.
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Follow with your favourite moisturiser.
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Use morning and evening as part of your daily skincare routine.
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During the daytime, finish with a broad-spectrum sunscreen.
💡 Pro Tips
Don't forget your neck
This serum is specifically formulated for both the face and neck, making it an excellent addition to a complete firming routine.
Layer from lightest to richest
Apply after toner and before moisturiser so the lightweight serum can absorb comfortably without feeling heavy.
Can it be used with Vitamin C or Retinol?
Medicube says yes. If you're introducing retinol, exfoliating acids, or other strong actives for the first time, add them gradually according to your skin's tolerance.
Great for oily skin too
Despite its firming and hydrating focus, the lightweight formula is non-comedogenic tested and designed to work across dry, oily, combination, and sensitive skin types.
Brand Clinical Testing
In Medicube's reported testing, the serum showed improvements in the appearance of smile lines and neck lines after two weeks, along with measured improvements in radiance across areas including the forehead, eye area, cheek, and corners of the mouth. Individual results may vary.

Ingredients: Water (Aqua), Butylene Glycol, Dipropylene Glycol, Niacinamide, Xylitol, 1,2-Hexanediol, Glycereth-26, Ectoin, Carbomer, C12-14 Alketh-12, Tromethamine, Ethylhexylglycerin, Theobroma Cacao (Cocoa) Seed Extract, Dextrin, Adenosine, Methyl Diisopropyl Propionamide, Disodium EDTA, Cyanocobalamin, Hydrogenated Phosphatidylcholine, sh-Oligopeptide-1, Glycerin, Rosa Canina Fruit Oil, Nicotinamide Adenine Dinucleotide, Xylitylglucoside, Anhydroxylitol, Sorbitan Laurate, Lecithin, Caprylyl Glycol, Polyglyceryl-10 Laurate, Hydroxyethylcellulose, Acetyl Glutamine, Acetyl Dipeptide-1 Cetyl Ester, Hydrogenated Lecithin, Bacillus/Soybean Ferment Extract, Vaccinium Vitis-Idaea Fruit Extract, Vaccinium Myrtillus Fruit Extract, Vaccinium Macrocarpon (Cranberry) Fruit Extract, Vaccinium Angustifolium (Blueberry) Fruit Extract, Ulmus Davidiana Root Extract, Sambucus Nigra Fruit Extract, Rubus Idaeus (Raspberry) Fruit Extract, Fragaria Vesca (Strawberry) Fruit Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Euterpe Oleracea Fruit Extract, Collagen Extract, Palmitoyl Tripeptide-5, Hibiscus Sabdariffa Flower Extract, Acetyl Hexapeptide-1, Acetyl Octapeptide-3, Sodium Hyaluronate, Folic Acid, Ficus Carica (Fig) Fruit Extract, Glutathione, Copper Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11
Ingredients subject to change at manufacturer's discretion. For the most complete and up-to-date list of ingredients, please refer to product packaging.